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Thursday, December 29, 2022

How Do Kidneys Impact Bone Health?

How Do Kidneys Impact Bone Health?

 

The kidneys are a vital organ for blood filtering and maintaining chemical balances. They also produce hormones, which regulate blood pressure and other processes.


Kidney function can be assessed by measuring a patient's creatinine clearance, which indicates how well that patient's kidneys filter waste products out of the bloodstream. In addition to their role in waste removal, kidneys regulate blood calcium levels, which is important for bone health.

The kidneys are a pair of bean-shaped organs besides the backbone and ribs on each side of the spine. They receive blood from the body's cardiovascular system, filter out wastes and excess water, and produce urine. Kidneys also produce hormones that regulate blood pressure, control salt levels, and help with red blood cell production.

The kidneys filter wastes from the blood, so they do not accumulate in the body or bloodstream.

What Is Mineral And Bone Disorder?

A mineral and bone disorder, also known as a metabolic disease, is a chronic condition that results in the body not having enough or too much of certain minerals. A genetic disorder may cause one type of mineral and bone disorder (such as osteoporosis), but an injury or disease causes others. Osteoporosis is the most common type of mineral and bone disorder.

Osteoporosis is a disease of the bones that causes them to become weak and prone to fractures. It usually affects older people but can also affect younger people who have been inactive for long periods or have taken certain medications.

Symptoms Of A Mineral And Bone Disorder

Mineral and bone disorders can be difficult to diagnose, depending on their cause, but they usually include the following symptoms:


  • Itchy skin
  • Bone pain
  • Weak bones that break easily
  • Blocked blood vessels
  • Heart problems
  • Anemia
  • Nerve problems
  • Difficulty fighting off germs

In general, mineral and bone disorders such as osteomalacia are not immediately life-threatening, but they can cause discomfort during everyday activities like sitting or walking for prolonged periods.

The Functions Of The Kidney In Maintaining Bone Structure

The kidney produces several hormones that play a part in maintaining bone structure. One such hormone, erythropoietin (EPO), stimulates the bone marrow to produce better red blood cells. Red blood cells carry oxygen throughout the body and are essential for healthy bones.

Renal Osteodystrophy

Renal osteodystrophy occurs when the bones are affected by a disease resulting from impaired kidney function. The kidneys regulate the blood levels of calcium and phosphate, which are necessary for bone growth. When these levels are not regulated properly, bone density is reduced, and renal osteodystrophy occurs.

Roles Of The Kidney In The Building, Remodeling, And Repair Of Bone



  • The kidney is an important organ for maintaining homeostasis of calcium and phosphate.

Kidneys eliminate excess amounts of calcium and phosphate, which are the building blocks of bones. If a person has a healthy diet, the kidneys can usually maintain a normal level of these minerals. A person might develop hypercalciuria or hyperphosphaturia if there is too much calcium and phosphate in the kidneys.

  • The kidney plays a role in regulating bone health by developing activated vitamin D.

The kidney regulates blood pressure, balances the production of salt and potassium, and controls the excretion of urine by the body.

"Additionally, it regulates bone health by generating activated vitamin D."

The kidneys can convert vitamin D into calcitriol, a metabolically active vitamin D, and release it into the bloodstream. This metabolized vitamin D is responsible for absorbing calcium and phosphorus in our diet.

  • The kidney produces a protein called Klotho, which supports bone formation and remodeling.

A hormone produced by the kidneys called klotho regulates bone formation and remodeling. A new study published in Cell Metabolism shows that this hormone also increases lifespan and combats aging-related diseases. The study found that klotho regulates the breakdown of bone tissue, which also plays a role in aging.

  • The kidneys regulate bone growth by producing the growth-inducing protein called bone morphogenetic protein 7.


A study published in Cell Reports has found that the protein BMP7, which the kidney produces, regulates bone growth by stimulating bone formation. Researchers found that when levels of BMP7 were reduced, mice experienced reduced bone length, size, and density. This discovery could have important implications for human diseases and disorders like rickets, osteogenesis imperfecta, osteoporosis, and arthritis.

A new study published in Cell Reports has shown that decreasing bone morphogenetic protein 7 (BMP7) results in smaller and lighter bones. The discovery may have important implications for the future of bone treatments.

  • The kidney synthesizes erythropoietin, a protein that promotes bone development and helps fractures heal.


The kidney produces erythropoietin (EPO), a hormone that stimulates the formation of red blood cells. These newly formed red blood cells deliver oxygen to the kidneys, bones, and muscles. Epoetin alpha is used to treat anemia caused by chronic kidney disease and other forms of anemia. Treatment with this drug has improved the quality of life for patients with severe anemia.

The Causes Of Chronic Kidney Disease That Affects Bone Health



Chronic kidney disease is a progressive, irreversible, and often fatal disease that causes a gradual loss of kidney function, leading to high blood pressure and anemia. It also puts sufferers at risk for bone health problems, including fractures and osteoporosis.

The causes of chronic kidney disease are not fully understood, but it is known that there are many factors involved. Diabetes, high blood pressure, Obesity, smoking, and other lifestyle choices are all risk factors for the disease.

How To Prevent Or Improve Chronic Kidney Disease To Protect Your Bones And Other Body Parts?

Chronic kidney disease can be affected by diabetes, high blood pressure, and chronic urinary tract infections. In addition, inherited diseases such as polycystic kidney disease can cause chronic kidney disease.

Here are some preventive measures that may help lower your risk of chronic kidney disease:

1. Be Physically Active


A healthy lifestyle includes regular physical activity. This reduces the risk of developing diseases, such as diabetes and heart disease, and helps increase overall health and well-being.

Before you begin an exercise program, it is important to determine which physical activity interests you most. Many recreational activities include walking, running, swimming and biking.

Consult with a physician before beginning any exercise program or when there is any possibility that your medical condition might make it difficult for you to engage in physical activity.

  1. Eat Healthily

There are many reasons why it can be difficult to make healthy food choices, including the availability of unhealthy options. In this section, you will discover tips for making healthier food choices.

The first step in making healthy food choices is to read nutrition labels and understand the nutritional content of the food you are considering. Knowing this information can help you identify if a food item has too much sugar or salt and make an informed decision about whether or not it is something you want to eat.

The second tip is to eat more vegetables and fruits because they contain few calories, lots of vitamins and minerals, and fiber which helps control your appetite.

According to a 2012 article in the journal Obesity, researchers found that drinking water before meals can increase feelings of fullness and lower caloric intake during meals. The more full you feel, the less likely you will overeat.

  1. Give Up Smoking And Alcohol

Craving is a powerful sensation that can lead people who want to quit smoking and drinking alcohol to relapse into their old habits. There are ways to reduce cravings, such as avoiding situations that trigger them and replacing bad habits with healthy ones.

It would be best if you tried to keep yourself busy and occupied by doing other things you enjoy. This will distract you from your cravings and help you not give in to them. It would also be best if you stayed away from people who smoke or drink alcohol because they will make your cravings stronger.

  1. Control Your Diabetes

Diabetes is a chronic disease that prevents the body from metabolizing sugar normally. It is either caused by insufficient insulin production by the pancreas or by unresponsive cells.

There are two types of diabetes, type 1 and type 2. Type 1 diabetes usually develops in childhood or adolescence and is caused by the body's immune system mistakenly attacking healthy cells in the pancreas. Type 2 is the most common form of diabetes, accounting for up to 95 percent of all cases.

The disease diabetes has a variety of symptoms, including increased thirst, hunger, frequent urination, blurred vision, slow healing wounds, and weight loss. The most common form is Type 2 diabetes. It accounts for 90% of all cases and usually occurs in adults over 40. The less common but still significant Type 1 diabetes generally starts in children or young adults and requires daily insulin injections to keep blood sugar levels under control.

The first step to controlling diabetes is to count your carbohydrates. Carbohydrates are present in starchy foods like bread, pasta, potatoes, and rice. The American Diabetes Association recommends limiting these foods to less than 20-25 grams per meal and 40-50 grams of carbs per day.

Before eating anything, measure your blood sugar levels and record the numbers on a sheet of paper for future reference. This will help you determine whether you need to consume fewer carbohydrates at certain times of the day or whether you need to administer more insulin.

  1. Control Your Blood Pressure

Several therapeutic diets are available for the treatment of hypertension. These diets include foods rich in potassium, magnesium, and calcium, such as bananas, avocados, broccoli, and spinach.

Another way to reduce sodium intake is to cut back on salt. People who try to reduce their salt intake by using a salt substitute or buying low-salt foods may find these methods ineffective. Avoiding processed foods and choosing whole foods such as fruits, vegetables, and grains is a better option.

  1. Manage Your Cholesterol

Cholesterol is a type of lipid in the blood and helps transport fat-soluble vitamins to cells throughout the body. It is also an important component of cell membranes, protecting from infection by bacteria and viruses. Eating healthy food low in saturated and trans fat can help lower cholesterol levels.

How Would I Know If I Have An Unhealthy Kidney Or Risk Factors That May Lead To Poor Bone Health?

It is important to speak to your doctor about possible kidney disease or bone health concerns if you experience any of the following symptoms.

Some of the common symptoms of kidney disease are:


  • Blood in the urine
  • Pain in the back, side, or abdomen
  • Frequent urination
  • Weight loss and fatigue.

Other risk factors for poor bone health include:


  • Osteoporosis (bone thinning)
  • Diet low in calcium and vitamin D.

Conclusion & Takeaway: What You Need To Know About The Link Between The Kidney And Bone Health

The kidneys regulate the amount of calcium and phosphate in the body. This is necessary for healthy bone formation. To maintain a healthy kidney function, you should always drink plenty of water and maintain a healthy diet with a surplus of calcium, vitamin D, and protein.

 

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